The electrical noise of a cell: correlations between resistance noise and voltage noise |
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| Affiliation: | 1. Department of Chemical Engineering, University of Bath, BA2 7AY, Bath, UK;2. Centre for Biosensors, Bioelectronics and Biodevices, University of Bath, BA2 7AY, Bath, UK;3. Department of Electronic and Electrical Engineering, University of Bath, BA2 7AY, Bath, UK |
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| Abstract: | A theory is developed for explaining the very low-frequency stochastic fluctuations of both the membrane voltage and the membrane conductance of a cell. It is shown that these fluctuations need not be correlated. However, in cells where the dominant transport mechanism is a potassium conductance, the theory predicts a significant negative correlation between the two with the relative fluctuations of the membrane conductance being much larger than those of the membrane voltage; this is in accord with previously published measurements. |
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