Urinary zinc excretion is normalized in primary arterial hypertension after perindopril treatment |
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Authors: | S?awomir Tubek |
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Institution: | (1) Faculty of Physical Education and Physiotherapy, Institute of Technology, Proszkowska 76, Opole, Poland;(2) Clinic of Cardiology, Medical Academy, Wroclaw, Proszkowska 76, 45-758 Opole, Poland |
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Abstract: | Increased or unchanged urinary zinc excretion has been reported in hypertension. In the present article, this observation
was confirmed in a group of 10 untreated hypertensive patients of both sexes that had no diabetes or obesity. The 24-h zinc
excretion was significantly different between the patients: 7.46±3.01 μmol and healthy controls: 5.19±2.19 μmol (p<0.025). After a 1-mo treatment with 4 mg perindopril per day, a decrease of urinary zinc was observed until it reached levels
not significantly different from those of the healthy controls (5.98±2.13 μmol). The decrease was significantly different
from that of the pretreatment values (p<0.05). |
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Keywords: | Zinc zinc urinary excretions arterial hypertension ACE inhibitors perindopril |
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