Circadian clock,cell cycle,and breast cancer: an updated review |
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Authors: | Armiya Sultan Arti Parganiha Tahira Sultan Vivek Choudhary Atanu Kumar Pati |
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Institution: | 1. Chronobiology and Animal Behaviour Laboratory, School of Life Sciences, Pt. Ravishankar Shukla University, Raipur, India;2. Center for Translational Chronobiology, Pt. Ravishankar Shukla University, Raipur, India;3. Department of Biochemistry, University of Kashmir, Srinagar, India;4. Regional Cancer Centre, Pt. J.N.M. Medical College, Dr. B.R. Ambedkar Memorial Hospital, Raipur, India |
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Abstract: | Some key elements are common to two fundamental periodic regulatory processes; the circadian cycle and the cell cycle. Underlying mechanisms of coordination between the two processes are critical for proper cellular functioning and physiology. Disruption in the mechanisms of one process may affect the role of other that may direct critical physiological changes and may cause severe diseases like cancer, etc. More or less persuasive evidences evolve from the breast cancer research. In this mini review, we highlighted the molecular coordination’s of the elements of circadian cycle and the cell cycle and their altered expressions associated with the genesis and progression of breast cancer. |
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Keywords: | Breast cancer cell cycle circadian cycle |
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