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CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA |
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| Authors: | Liz J Hernandez-Borrero Shengliang Zhang Amriti Lulla David T Dicker |
| Institution: | Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Department of Medical Oncology and Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, USA |
| Abstract: | |
| Keywords: | apoptosis autophagy mutant p53 degradation NOXA p53 pathway restoration ubiquitin proteasome system |