恶性肿瘤患者合并感染临床分析

目的：探讨肿瘤患者合并感染常见病原菌的分布及对抗生素的敏感性。方法：回顾性总结分析139例恶性肿瘤患者合并感染的标本细菌培养及药敏情况。结果：112例细菌学检查阳性的患者感染部位以呼吸道最多，占69.6%，153份标本共检出122株细菌，其中真菌48株，占39.3%；G^-杆菌38株，占31.1%；G^ 球菌36株，占29.5%。所检出的葡萄球菌对万古霉素，新霉素较敏感，大肠埃希菌对阿米卡星31.1%；G^ 球菌36株，占29.5%，所检出的葡萄球菌对万古霉素，新霉素较敏感，大肠埃然菌对阿米卡星敏感，铜绿假单胞菌对环丙沙星尚敏感，其余抗生素对病原菌均呈现不同程度的耐药，结论：肿瘤患者合并感染的病原菌主要为条件致病菌，而且有较严重的耐药情况，临床治疗应重视病原学检查，合理使用抗生素，减少耐药菌株的产生和内源性感染。

ANALYSIS TO INFECTION OF CANAER PATIENTS

Objective:To study the distribution of pathogens in infection of cancer patients and the resistance to antimicrobial drugs.Methods: 139 cases of cancer patients with infection were analyzed for infection bacteria and resistance to drugs. Results: The majority had respiratory tract infection(69 6%).122 strains of pathogens were isolated from 153 cultures of specimens in which there were 48 strains of fungi(39 3%),38 straits of Gram negative bacilli (31 1%) and 36 straits of Gram positive cocci(29 5%) Gram positive cocci had highter susceptibility rate to Norvancimycin,neomycin.E.Coli had hight susceptibility rate to amikacin.P.aesuginosa had hight susceptibility rate to ciprofloxacin. Conclusion: The opportunity pathogens were main cause for infection of cancer patients.The resistance to drugs was serious.Rational use of antimicrobial drugs should be emphasised during clinical therapy to decrease multiresistant to antibiotics.