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MicroRNA-dependent targeting of the extracellular matrix as a mechanism of regulating cell behavior

Authors:	Sherif Abdelaziz Ibrahim,Hebatallah Hassan,Martin Gö tte

Affiliation:	1. Department of Zoology, Faculty of Science, Cairo University, Giza 12613, Egypt;2. Department of Gynecology and Obstetrics, Münster University Hospital, Albert-Schweitzer-Campus 1, D11, 48149 Münster, Germany

Abstract:

Keywords:	ceRNA, competing endogenous RNA ECM, extracellular matrix EMT, epithelial-to-mesenchymal transition FAK, focal adhesion kinase FGF, fibroblast growth factor HS, Heparan sulfate HSPG2, heparan sulfate proteoglycan 2, perlecan IL, interleukin LDL, Low density lipoprotein miRNA, microRNA MMP, matrix metalloproteinase NDST1, N-deacetylase/N-sulfotransferase-1 NF-κB, nuclear factor-κB PAI-1, plasminogen activator inhibitor-1 SMC, Smooth muscle cell SNP, single nucleotide polymorphism SPARC, Secreted protein acidic and rich in cysteine TIMP, tissue inhibitor of metalloproteinase TNF, tumor necrosis factor uPAR, urokinase-type plasminogen activator receptor UTR, untranslated region VEGF, vascular endothelial growth factor
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