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Adaptive responses to glucose restriction enhance cell survival,antioxidant capability,and autophagy of the protozoan parasite Trichomonas vaginalis
Authors:Kuo-Yang Huang  Yi-Ywan Margaret Chen  Yi-Kai Fang  Wei-Hung Cheng  Chih-Chieh Cheng  Yu-Chuen Chen  Tiffany E Wu  Fu-Man Ku  Shih-Chieh Chen  Rose Lin  Petrus Tang
Institution:1. Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan;2. Molecular Regulation and Bioinformatics Laboratory, Department of Parasitology, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan;3. Bioinformatics Center, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan;4. Department of Microbiology and Immunology, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan
Abstract:
Keywords:GR  glucose restriction  CR  caloric restriction  NGS  next generation sequencing  RNA-seq  RNA sequencing  GK  Glucokinase  GPI  Glucose phosphate isomerase  PFK  Phosphofructokinase  ALDO  Fructose-1  6-bisP aldolase  TPI  Triose-phosphate isomerase  GAPDH  Glyceraldehyde 3-P dehydrogenase  PGK  Phosphoglycerate kinase  PGAM  phosphoglycerate mutase  ENO  Enolase  PEPCK  Phosphoenolpyruvate carboxykinase  MDH  Malate dehydrogenase  PK  Pyruvate kinase  ME  Malic enzyme  ALT  Alanine aminotransferase  ADH  Alcohol dehydrogenase  LDH  Lactate dehydrogenase  GDH  Glutamate dehydrogenase  SOD  Superoxide dismutase  TrxP  Thioredoxin peroxidase  Rbr  rubrerythrin  ROS  reactive oxygen species
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