Teratocarcinogenesis as related to the age of embryos grafted under the kidney capsule |
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| Authors: | Dr Ivan Damjanov Davor Solter Nikola Škreb |
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| Institution: | (1) Institute of Biology, University of Zagreb, Croatia;(2) Department of Pathology, Medical Faculty,  alata 10, 41000 Zagreb, Yugoslavia |
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| Abstract: | Summary Mouse egg-cylinders of C3H/H strain with two and three germ layers were transplanted under the kidney capsule. They developed into well differentiated teratomas and teratocarcinomas. Older embryos developed invariably into teratomas composed of adult tissues only. We consider the period of germ layer inversion as a critical stage when embryonic cells loose their potentiality for uncontrolled growth. |
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