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牛磺熊去氧胆酸的合成进展
引用本文:王鹏,朱荣菊.牛磺熊去氧胆酸的合成进展[J].氨基酸和生物资源,2013,35(2):46-50.
作者姓名:王鹏  朱荣菊
作者单位:延安大学西安创新学院,陕西西安,710100;延安大学西安创新学院,陕西西安,710100
摘    要:牛磺熊去氧胆酸是由熊去氧胆酸的羧基和牛磺酸的氨基之间缩水而形成的结合型胆汁酸。主要介绍了目前四种牛磺熊去氧胆酸合成方法,并对四种方法的优缺点进行了全面的评价,从而为牛磺熊去氧胆酸的合理开发和利用提供思路。

关 键 词:牛磺熊去氧胆酸  熊去氧胆酸  牛磺酸  合成

Progress on Synthesis of Tauroursodeoxycholic Acid
WANG Peng,ZHU Rongju.Progress on Synthesis of Tauroursodeoxycholic Acid[J].Amino Acids & Biotic Resources,2013,35(2):46-50.
Authors:WANG Peng  ZHU Rongju
Institution:(Xian Innovation College,Yanan University,Xian 710100,Shaanxi,China)
Abstract:Tauroursodeoxycholic acid is a kind of conjugated bile acids which is dehydrated by carboxy group from ursodeoxycholic acid and amino group from taurine.Four current synthetic methods of tauroursodeoxycholic acid are introduced,and advantages and disadvantages are evaluated.Furthermore some ideas are provided for the rational development and utilization of tauroursodeoxycholic acid.
Keywords:tauroursodeoxycholic acid  ursodeoxycholic acid  taurine  synthesis
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