Abstract: | Different P. aeruginosa strains have been found to differ in exotoxin synthesis. The strain isolated at the Mechnikov Research Institute for Vaccines and Sera (Moscow) and newly isolated cultures obtained from patients with the severe course of the infectious process have been found to possess the highest toxigenic activity and to synthesize exotoxins with the most complete set of pathogenically important antigens. The technological scheme for the production of stable exotoxin which can be used for the development of diagnostic, therapeutic and prophylactic preparations against Pseudomonas infections is proposed. |