Sensitivity enhancement of DNA sensors by nanogold surface modification |
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| Authors: | Liu Tao Tang Ji'an Jiang Long |
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| Institution: | Laboratory of Colloid and Interface Science, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Science, Beijing 100080, People's Republic of China. |
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| Abstract: | A novel amplified microgravimetric gene sensing system was developed using quartz crystal microbalance modified by gold nanoparticles anchored on its 1,6-hexanedithiol modified gold electrode surface, and ultrasensitive detection of DNA hybridization was accomplished at the level of at least 2 x 10(-16) M. |
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| Keywords: | Colloidal Au DNA sensing Quartz crystal microbalanace |
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