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乙型肝炎病毒全基因序列的测定
引用本文:郭亚兵,侯金林,戴炜.乙型肝炎病毒全基因序列的测定[J].中国病毒学,1999,14(3):1896-1.
作者姓名:郭亚兵  侯金林  戴炜
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Sequencing of the Whole Gene of Hepatitis B Virus
Abstract:Seven cases of chronic hepatitis B virus carriers were included for sequencing of whole gene sequences of hepatitis B virus (HBV). The serotype of 4 strains of HBV were adr, and 3 strains were adw. Two strains were classified to genotype B, and the other 5 strains to genotype C. No significant mutations, such as A1896, T1762A1764 were present. With other reported 2 complete sequences of HBV strains prevailing in mainland China, 7 strains of HBV whole sequences of genotype C from mainland China were analyzed to produce the consensus sequence of HBV of China. Comparing of the consensus sequence with that from Genbank, there were only 22 sites with different nucleotides.
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