Survival quantitative trait locus fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium |
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| Authors: | Casellas J |
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| Institution: | Grup de Recerca en Remugants, Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. joaquim.casellas@irta.es |
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| Abstract: | I show that fine-scale localization of a survival-related locus can be accomplished on the basis of deviations from Hardy-Weinberg equilibrium and linkage disequilibrium at closely linked marker loci. The method is based on chi(2)-tests and they can be performed for age-specific samples of alive (or dead) individuals, as for combined samples of alive and dead individuals. |
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