| Abstract: | From the bulbs of Crinum pratense, collected at flowering, lycorine, 1,2-diacetyllycorine, ambelline, narcissidine, and three phenanthridone alkaloids, viz. hippadine, pratorinine and anhydrolycorin-7-one, were isolated and characterized on the basis of comprehensive spectral analyses (UV, IR, 1H NMR, 13C NMR, MS, α]D) and chemical evidence. Among the phenanthridone alkaloids (1–3, only the natural occurrence of hippadine was previously known. Pratorinine is a new phenanthridone alkaloid and anhydrolycorin-7-one was known before only as a synthetic compound. The physiological significance of hippadine is appraised. |
