Bactericidal effect of rat cystatin S on an oral bacterium Porphyromonas gingivalis |
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| Institution: | 1. Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, 467, Japan;2. Medical School, Nagoya City University, Nagoya, 467, Japan;3. Department of Oral Microbiology, Ashahi University School of Dentistry, Gifu, 501-02, Japan;4. Aichi Prefectural Institute of Public Health, Nagoya, 467, Japan;1. School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang 550000, China;2. Engineering Research Centre of Fujian-Taiwan Special Marine Food Processing and Nutrition of Ministry of Education, College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China;3. Meat Processing Key Laboratory of Sichuan Province, School of Food and Biological Engineering, Chengdu University, Chengdu, Sichuan 610106, China;4. College of Food Science, Tibet Agriculture and Animal Husbandry University, Linzhi, Tibet Autonomous Region 860000, China;1. Department of Exercise Sciences, Université du Québec à Montréal, Montréal, Québec, Canada;2. Department of Food Science, Université Laval, Montréal, Québec, Canada;3. Institut de Nutrition et des Aliments Fonctionnels, Université Laval, Montréal, Québec, Canada;4. Department of Kinesiology, McGill University, Montréal, Québec, Canada;5. Department of Kinesiology, Université de Montréal, Montréal, Québec, Canada;6. CHU Sainte-Justine Research Center, Université de Montréal, Montréal, Québec, Canada;1. College of Food Science and Engineering, Ocean University of China, 266003 Qingdao, China;2. School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China;3. Quzhou Sturgeon Aquatic Food Science and Technology Development Co., Ltd., Quzhou 324002, China;4. College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China |
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| Abstract: | We tested antibacterial and antiviral activities of rat cystatin S, a cysteine proteinase inhibitor, belonging to the family 2 cystatins against 18 different bacterial species and poliovirus type 1 (Sabin). Rat cystatin S specifically inhibited the growth of a human oral anaerobic bacterium Porphyromonas gingivalis due to a bactericidal effect. |
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