At the crossroads of chemistry and biology |
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Authors: | Waldmann H |
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Affiliation: | Max-Planck-Institut für molekulare Physiologie, Abt. Chemische Biologie, Otto-Hahn-Str. 11, D-44227 Dortmund, Germany. herbert.waldmann@mpi-dortmund.mpg.de |
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Abstract: | The life sciences are molecular and the harnessing of information gleaned from genomics and proteomics will require interdisciplinary research integrating chemistry and biology. This approach is illustrated by the synthesis and biological evaluation of lipidated peptides and proteins and the delineation of a concept arguing for natural product guided combinatorial chemistry. |
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