|
|||||
|
|
Molecular Dissection of the Basal Clades in the Human Y Chromosome Phylogenetic Tree |
|
| Authors: | Rosaria Scozzari Andrea Massaia Eugenia D’Atanasio Natalie M. Myres Ugo A. Perego Beniamino Trombetta Fulvio Cruciani |
| Affiliation: | 1. Dipartimento di Biologia e Biotecnologie “Charles Darwin”, Sapienza Università di Roma, Rome, Italy.; 2. Sorenson Molecular Genealogy Foundation, Salt Lake City, Utah, United States of America.; 3. AncestryDNA, Provo, Utah, United States of America.; 4. Dipartimento di Biologia e Biotecnologie “Lazzaro Spallanzani”, Università di Pavia, Pavia, Italy.; University of Florence, Italy, |
| Abstract: | One hundred and forty-six previously detected mutations were more precisely positioned in the human Y chromosome phylogeny by the analysis of 51 representative Y chromosome haplogroups and the use of 59 mutations from literature. Twenty-two new mutations were also described and incorporated in the revised phylogeny. This analysis made it possible to identify new haplogroups and to resolve a deep trifurcation within haplogroup B2. Our data provide a highly resolved branching in the African-specific portion of the Y tree and support the hypothesis of an origin in the north-western quadrant of the African continent for the human MSY diversity. |
| Keywords: | |