Analysis of HIV-1 drug resistant mutations by line probe assay and direct sequencing in a cohort of therapy naive HIV-1 infected Italian patients |
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Authors: | Maria Carla Re Paola Monari Isabella Bon Davide Gibellini Francesca Vitone Marco Borderi Michele La Placa |
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Institution: | (1) Department of Microbiology, Immunology & Parasitology, Neuroscience Center of Excellence and Stanley S. Scott Cancer Center, Louisiana State University Medical Center, 70112-1393 New Orleans, LA, USA;(2) Division of Virology, Department of Neuropharmacology, The Scripps Research Institute, 92037 La Jolla, California, USA |
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Abstract: | Background Recent studies of viral entry proteins from influenza, measles, human immunodeficiency virus, type 1 (HIV-1), and Ebola virus have shown, first with molecular modeling, and then X-ray crystallographic or other biophysical studies, that these disparate viruses share a coiled-coil type of entry protein. |
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