A computer program to display codon changes caused by mutagenesis |
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Authors: | Sirotkin Karl |
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Affiliation: | Theoretical Division, Group T-10, Mail Stop K710, Los Alamos National Laboratory Los Alamos, NM 87545 Department of Microbiology and Graduate Program in Cellular, Molecular and Developmental Biology, University of Tennessee Knoxville, TN 37996-0845, USA |
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Abstract: | A FORTRAN program for displaying the correspondence betweencodon changes and different possible base changes is presented.Changes of both single bases and dimers are considered. Theuser can specify the mutagenesis spectrum. Additionally, theuser can choose whether or not to consider single or doubleevents in a codon and whether or not to consider the possibilitythat the change of two bases (a dimer) can overlap a codon boundary.Furthermore, a variety of ways may be chosen to display andsummarize the codon changes that can result from the specifiedmutagenesis. A user-supplied sequence or the genetic code tablecan be analyzed. Received on January 27, 1987; accepted on September 4, 1987 |
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