Cloning and nucleotide sequence of cDNA encoding human erythrocyte band 7 integral membrane protein |
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| Authors: | C M Hiebl-Dirschmied B Entler C Glotzmann I Maurer-Fogy C Stratowa R Prohaska |
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| Affiliation: | Institute of Biochemistry, University of Vienna, Austria. |
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| Abstract: | cDNA clones encoding the human erythrocyte band 7 membrane protein were isolated by immunoscreening from bone marrow and HeLa cell lambda gt 11 cDNA libraries, and their nucleotide sequences were determined. HeLa- and bone marrow cell-derived sequences were identical, except for one nucleotide; the deduced sequence of 287 amino acids was confirmed by sequence identity with peptides of the erythroid protein. Structure analysis assigned band 7 protein to the type Ib transmembrane proteins. |
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