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Obesity and liver cancer mortality in Asia: The Asia Pacific Cohort Studies Collaboration
Authors:G David Batty  Federica Barzi  Rachel Huxley  Charissa Y Chang  Sun Ha Jee  Konrad Jamrozik  Hyeon Chang Kim  Xianghua Fang  Tai H Lam  Mark Woodward
Institution:1. Department of General, Visceral and Transplant Surgery, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany;2. Institute of Medical Statistics, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany;3. Department of Surgery, Maastricht University Medical Center, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands;4. Department of Radiology, Zuyderland Medical Centre, Heerlen, the Netherlands;5. Department of Radiology, Maastricht University Medical Centre, Maastricht, the Netherlands
Abstract:While obesity is associated with liver cancer in studies from western societies, the paucity of data from Asia limits insights into its aetiological role in this population. We examined the relationship between body mass index (BMI) and liver cancer mortality using data from the Asia Pacific Cohort Studies Collaboration. In 309,203 Asian study members, 4 years of follow-up gave rise to 11,135 deaths from all causes, 420 of which were ascribed to liver cancer. BMI, whether categorised according to current guidelines for Asian groups or World Health Organisation recommendations, was not associated with liver cancer in any of our analyses.
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