Norbergenin derivatives from the stem bark of Diospyros sanza-minika (Ebenaceae) and their radical scavenging activity |
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| Authors: | Jean Gustave Tangmouo Raimana Ho Alain Meli Lannang Justin Komguem Axel Tiwa Lontsi David Lontsi Kurt Hostettmann |
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| Institution: | 1. Department of Organic Chemistry, University of Yaoundé I, P.O. Box 812 Yaoundé, Cameroon;2. Laboratory of Pharmacognosy and Phytochemistry, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest-Ansermet 30, CH-1211 Geneva 4, Switzerland;3. Department of Chemistry, Higher Teachers’ Training College, University of Maroua, P.O. Box 46 Maroua, Cameroon |
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| Abstract: | Three new norbergenin derivatives, 11-O-p-hydroxybenzoylnorbergenin, 4-O-(3′-methylgalloyl)norbergenin and 4-O-syringoylnorbergenin were isolated from the stem bark of Diospyros sanza-minika, along with three known compounds: norbergenin, 4-O-galloylnorbergenin and quercitol. Their structures were established on the basis of 1D and 2D NMR experiments and mass spectrometry. Some of the above compounds showed radical scavenging properties in a DPPH solution assay. |
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