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Diterpene content of the alga Dictyota ciliolata from a Moroccan lagoon
Authors:Emiliano Manzo  M Letizia Ciavatta  Salem Bakkas  Guido Villani  Mario Varcamonti  Anna Zanfardino  Margherita Gavagnin
Institution:1. Istituto di Chimica Biomolecolare, CNR, Via Campi Flegrei 34, I 80078 Pozzuoli (Naples), Italy;2. Universitè Chouaib Doukkali, Facultè des Sciences, Km 1, Route de Ben Maachou, B.P. 20, 24000-El Madida, Morocco;3. Dipartimento di Biologia Strutturale e Funzionale, Università di Napoli Federico II, Via Cinthia, I 80100 Naples, Italy
Abstract:Analysis of the secondary metabolites content of the brown alga Dictyota ciliolata, collected from Oualidia lagoon (Morocco), revealed the presence of xenicane and guaiane homologous diterpenes. Two new xenicanes, 1 and 2, co-occurring with the known dictyodial, dictyol C and dictyol H, have been isolated and characterized by spectral methods, mainly by NMR techniques. Compound 2 displayed mild antifungal activity against Candida albicans.
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