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Primary malignant tumors of orofacial region at Benghazi,Libya: A 17 years review
Authors:Krishnaraj Subhashraj  Maraai Orafi  K.V. Nair  Rafa El-Gehani  Mohammed Elarbi
Affiliation:1. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Al-Arab Medical Science University, Benghazi, Libya;2. Department of Oral and Maxillofacial Surgery, Al-Fatah University, Tripoli, Libya;1. Department of Pathology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, PR China;2. Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, PR China;3. Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, PR China;1. School of Health Sciences, University of Tampere, Tampere, Finland;2. Tampere University Hospital, Lahti Unit of Radiation Therapy, Lahti, Finland;3. Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway;4. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden;5. Icelandic Cancer Registry, Reykjavik, Iceland;6. Faculty of Medicine, University of Iceland, Reykjavik, Iceland;7. Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki, Finland;8. Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway;9. Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland;1. Department of Comprehensive Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan;2. Department of Hematology, Japanese Red Cross Medical Centre, Tokyo, Japan;1. Unit of Oral and Maxillofacial Pathology, The School of Clinical Dentistry, Sheffield, UK;2. Consultant Histopathologist, Histopathology Department, Royal Derby Hospital, Derby, UK;3. Professor in Oral and Maxillofacial Pathology, Honorary Consultant Histopathologist and Dean of Clinical Dentistry, Unit of Oral and Maxillofacial Pathology, The School of Clinical Dentistry, Sheffield, UK;1. Unidad de Investigación Médica en Enfermedades Infecciosas, Hospital de Pediatría, Instituto Mexicano del Seguro Social, Centro Médico Nacional SXXI, Mexico, D.F., Mexico;2. Departamento de Patología, Hospital Infantil de México Federico Gómez, Secretaría de Salud, Mexico, D.F., Mexico;3. Departamento de Genética, Hospital General de México, Secretaría de Salud, Mexico, D.F., Mexico
Abstract:The aim of this study was to systematically analyze the clinical presentations of orofacial malignant tumors in a Libyan population over a period of 17 years and compare the results with the reports from other countries. During the study period, tumors of epithelial origin were found in 160 patients (82%), followed by tumors of immune system, 22 (11%) and tumors of mesenchymal origin, 14 (7%). Of the total malignant tumors, 115 were men and 81 were women and the male to female ratio was 1.41:1. Malignant non-odontogenic tumors were seen in 194 patients (99%) and malignant odontogenic tumors were seen in 2 patients (1%). Among the epithelial tumors, squamous cell carcinoma (50.6%) was the most common neoplasm, followed by mucoepidermoid carcinoma (15%) and adenoid cystic carcinoma (8.7%). The incidence of oral malignancy is impressively low with respect to the corresponding levels in other countries in Africa and some European countries.
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