Nocturnal polysomnographic characteristics of pediatric narcolepsy |
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Authors: | Rao Satish C. Mansukhani Meghna P. Lloyd Robin M. Slocumb Nancy L. Kotagal Suresh |
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Affiliation: | 110.Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky, USA ;210.Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota, 40292, USA ; |
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Abstract: | The aim of this study was to describe the polysomnographic features of childhood-onset narcolepsy. A retrospective review was performed on children with narcolepsy. The polysomnogram findings were compared with reference values obtained from normative data in the general population. Narcolepsy subjects had a mean initial sleep latency of 10.9 min on nocturnal PSG, which was shorter by a mean of 18 min than corresponding values from normative data (P < 0.001). Short initial REM latency on nocturnal PSG correlated with the number of SOREMPs on MSLT in subjects with narcolepsy (P = 0.007). These findings may assist in the clinical diagnosis of narcolepsy. |
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