First International Workshop on Porcine Chromosome 6 |
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| Authors: | A A Paszek LB Schook C F Louis JR Mickelson G H Flickinger J Murtaugh J R Mendiola M A Janzen C W Beattie G A Rohrer L J Alexander L Andersson H Ellegren M Johansson P Mariani L Marklund B Høyheim W Davies M Fredholm A L Archibald C S Haley |
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| Institution: | Department of Veterinary Patho Biology, University of Minnesota, 1988 Fitch Ave, 295 AS/VM Bldg., St. Paul, MN, 5108USA;Workshop Chair;USDA, ARS, Roman L. Hruska U. S. Meat Animal Research Center (MARC), Clay Center, Nebraska 68933 USA;Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Box 597, S-751 24 Uppsala, Sweden;Department of Biochemistry, Physiology and Nutrition, Norwegian College of Veterinary Medicine, PO Box 8146 Dept, N-0033 Oslo, 1, Norway;Department of Animal Production and Animal Health, Division of Animal Genetics, The Royal Veterinary and Agricultural University, Bülowsvej 13, DK-1870 Frederiksberg C, Copenhagen, Denmark;Roslin Institute (Edinburgh), Roslin, Midlothian EH25 9PS, UK |
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| Abstract: | Recent advances in the use of microsatellite markers and the development of comparative gene mapping techniques have made the construction of high resolution genetic maps of livestock species possible. Framework and comprehensive genetic linkage maps of porcine chromosome 6 have resulted from the first international effort to integrate genetic maps from multiple laboratories. Eleven highly polymorphic genetic markers were exchanged and mapped by four independent laboratories on a total of 583 animals derived from four reference populations. The chromosome 6 framework map consists of 10 markers ordered with high local support. The average marker interval of the framework map is 15.1 cM (sex averaged). The framework map is 135, 175 and 109 cM in length (for sex averaged, female and male maps, respectively). The comprehensive map includes a total of 48 type I and type II markers with a sex averaged interval of 3.5 cM and is 166, 196 and 126 cM (for sex averaged, female and male maps, respectively). Additional markers within framework map marker intervals can thus be selected from the comprehensive map for further analysis of quantitive trait loci (QTL) located on chromosome 6. The resulting maps of swine chromosome 6 provide a valuable tool for analysing and locating QTL. |
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| Keywords: | comprehensive maps framework map integrated linkage map swine chromosome 6 |
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