Detection of Balamuthia mandrillaris DNA by real-time PCR targeting the RNase P gene |
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| Authors: | Albrecht F Kiderlen Elke Radam Astrid Lewin |
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| Affiliation: | (1) Robert Koch Institute, Cellular Immunology Unit P22, Nordufer 20, 13353 Berlin, Germany |
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| Abstract: | Background The free-living amoeba Balamuthia mandrillaris may cause fatal encephalitis both in immunocompromised and in - apparently - immunocompetent humans and other mammalian species. Rapid, specific, sensitive, and reliable detection requiring little pathogen-specific expertise is an absolute prerequisite for a successful therapy and a welcome tool for both experimental and epidemiological research. |
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