Host range of obligate intracellular bacterium Parachlamydia acanthamoebae |
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Authors: | Hayashi Yasuhiro Nakamura Shinji Matsuo Junji Fukumoto Tatsuya Yoshida Mitsutaka Takahashi Kaori Mizutani Yoshihiko Yao Takashi Yamaguchi Hiroyuki |
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Affiliation: | Department of Medical Laboratory Sciences, Hokkaido University Graduate School of Health Sciences, Sapporo, Hokkaido 060-0812, Japan. |
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Abstract: | The obligate intracellular bacterium Parachlamydia acanthamoebae is a potential human pathogen, but the host range of the bacteria remains unknown. Hence, the growth of P. acanthamoebae Bn9 in protozoa (Tetrahymena, Acanthamoeba, Dictyostelium) and mammalian cells (HEp‐2, Vero, THP‐1, PMA‐stimulated THP‐1, Jurkat) was assessed using an AIU assay which had been previously established by the current authors. P. acanthamoebae grew in Acanthamoeba but not in the other cell types. The growth was also confirmed using DAPI staining, FISH and TEM. These results indicate that the host range of P. acanthamoebae is limited. |
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Keywords: | AIU assay host range Parachlamydia acanthamoebae protozoa |
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