mTOR Signaling Fades POMC Neurons during Aging |
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| Authors: | Jae Geun Kim Tamas L Horvath |
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| Affiliation: | Program in Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New?Haven, CT 06520, USA. |
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| Abstract: | Hypothalamic POMC neurons contribute to the regulation of energy homeostasis and glucose metabolism. In this issue of Neuron, Yang et?al. (2012) show that the mTOR pathway has a pivotal role in deterioration of POMC neurons during age-dependent obesity. |
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