|
|||||
|
|
Functional magnetic resonance imaging of the primary motor cortex in humans: response to increased functional demands |
|
| Authors: | S Khushu S S Kumaran R P Tripathi A Gupta P C Jain V Jain |
| Institution: | (1) NMR Research Centre, Institute of Nuclear Medicine and Allied Sciences, Lucknow Road, 110 054 Delhi, India;(2) Department of Physics and Astrophysics, University of Delhi, 110 007 Delhi, India;(3) BR Ambedkar Centre for Biomedical Research, University of Delhi, 110 007 Delhi, India;(4) Present address: Wallace-Kettering Neuroscience Institute, Kettering Medical Centre and Department of Emergency Medicine, Wright State University, 45429 Kettering, OH, USA |
| Abstract: | Functional magnetic resonance imaging (fMRI) studies have been performed on 20 right handed volunteers at 1.5 Tesla using echo planar imaging (EPI) protocol. Index finger tapping invoked localized activation in the primary motor area. Consistent and highly reproducible activation in the primary motor area was observed in six different sessions of a volunteer over a period of one month. Increased tapping rate resulted in increase in the blood oxygenation level dependent (BOLD) signal intensity as well as the volume/area of activation (pixels) in the contra-lateral primary motor area up to tapping rate of 120 taps/min (2 Hz), beyond which it saturates. Activation in supplementary motor area was also observed. The obtained results are correlated to increased functional demands. |
| Keywords: | Echo-planar imaging finger tapping frequency functional demand functional magnetic resonance imaging primary motor cortex |
| 本文献已被 SpringerLink 等数据库收录！ | |