Early pattern formation in the developing Drosophila eye |
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Authors: | Thomas B J Zipursky S L |
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Institution: | Department of Biological Chemistry, University of California, Los Angeles, CA 90024, USA. |
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Abstract: | The formation of complex cellular arrays from unpatterned epithelia is a widespread developmental phenomenon. Insights into the mechanisms regulating this transformation have come from studying the development of the Drosophila compound eye. Pattern formation in the eye primordium is a highly ordered process in which the onset of differentiation is coordinated with synchronization of cell cycle progression. Recent studies have identified a number of genes that are required for early patterning events, and provide a link between the regulation of proliferation and pattern formation. |
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