| 血清降钙素原检测对早期诊断新生儿败血症的临床价值 |
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| 引用本文： | 朱江丽 朱兵 王秉林 田广磊. 血清降钙素原检测对早期诊断新生儿败血症的临床价值[J]. 现代生物医学进展, 2011, 11(21): 4126-4128 |
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| 作者姓名： | 朱江丽 朱兵 王秉林 田广磊 |
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| 作者单位： | 1. 新疆医科大学附属中医医院检验科 新疆乌鲁木齐830001
2. 新疆维吾尔自治区人民医院血管外科 新疆乌鲁木齐830001 |
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| 摘 要： | 目的:探讨血清降钙素原(PCT)作为早期诊断新生儿败血症指标的临床价值。方法:应用免疫色谱法对101例新生儿进行PCT水平测定,并与C反应蛋白(CRP)作比较。将患儿按出院诊断分为败血症组、一般感染组、非感染组进行分析。结果:败血症组患儿血清PCT和CRP明显高于一般感染组和非感染组,差异有统计学意义(P<0.05);一般感染组与非感染组血清PCT、CRP比较差异有统计学意义(P<0.05)。以0.5ng/mL为临界值,PCT诊断新生儿败血症的敏感度为92.11%,特异度为78.79%;以8.0mg/L为临界值,诊断败血症的敏感度为65.79%,特异度为69.70%。与CRP相比,PCT诊断败血症的敏感性、特异性更高。经有效抗生素治疗后,血清PCT下降幅度明显大于血清CRP下降幅度。结论:新生儿血清中PCT水平的检测对败血症的早期诊断及病情程度判断、治疗效果的评价具有重要价值。
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| 关 键 词： | 降钙素原 C反应蛋白 新生儿 败血症 诊断 |
The Value of Serum Procalcitonin in the Early Diagnosis of NeonatalSepticemia |
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| ZHU Jiang-li,ZHU bing,WANG Bing-lin,TIAN Guang-lei. The Value of Serum Procalcitonin in the Early Diagnosis of NeonatalSepticemia[J]. Progress in Modern Biomedicine, 2011, 11(21): 4126-4128 |
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| Authors: | ZHU Jiang-li ZHU bing WANG Bing-lin TIAN Guang-lei |
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| Affiliation: | 1 Xinjiang medical college accessory of traditional Chinese hospital department of Clinical Laboratory,Xinjiang Urumqi 830001; 2 Xinjiang Uygur Autonomous Region people hospital department of Cardiovascular Surgery,Xinjiang,Urumqi 830001) |
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| Abstract: | Objective: To investigate Procalcitonin(PCT) for early diagnosis of neonatal septicemia.Methods: The serum PCT levels were measured with immune chromatography(PCT-Q) assay and compared with the serum C-reactive protein(CRP) in 101 neonates.To assignment the neonates for three groups with discharage diagnosis,101 neonates were divided into neonatal septicemia group,common infection group and non-infection group according to discharge diagnosis.Results: Serum concentrations of PCT and CRP in neonatal septicem... |
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| Keywords: | Procalcitonin C-reactive protein Neonatal Septicemia Diagnose |
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