| 血浆IIA 分泌型磷脂酶A2 水平与冠脉支架术后再狭窄关系 |
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| 引用本文： | 高应东 夏永祥 张瑞生 朱成宾 赵昕亚 肖平喜. 血浆IIA 分泌型磷脂酶A2 水平与冠脉支架术后再狭窄关系[J]. 现代生物医学进展, 2011, 11(19): 3666-3668 |
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| 作者姓名： | 高应东 夏永祥 张瑞生 朱成宾 赵昕亚 肖平喜 |
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| 作者单位： | 1. 南京医科大学附属南京第一医院检验科 江苏南京 210006
2. 南京医科大学附属南京第一医院心内科 江苏南京 210006 |
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| 摘 要： | 目的:测定稳定型冠心病患者支架植入术(percutanous coronary intervention,PCI)前血浆IIA分泌型磷脂酶A2(group IIAsecretory phospholipase A2,ⅡA-sPLA2)的水平,以探讨该酶与冠脉支架术后再狭窄的可能关系。方法:稳定型冠心病行PCI患者63例,非冠心病患者39例,健康正常对照组42例,分别取外周静脉血测定血浆ⅡA-sPLA2酶浓度。PCI患者6个月后复查造影。结果:PCI患者术前该酶浓度显著高于正常对照组(P<0.05),支架内再狭窄率34.9%,再狭窄(restenosis,RS)患者支架术前该酶水平与无再狭窄患者该酶水平无统计学差异(P>0.05)。结论:PCI患者术前血浆ⅡA-sPLA2酶浓度显著高于正常对照组,但可能与支架术后再狭窄无关。
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| 关 键 词： | ⅡA分泌型磷脂酶A2 高敏C-反应蛋白 支架植入术 再狭窄 |
Relationship Between Plasma IIA Secretory Phospholipase A2 andRestenosis after Percutanous Coronary Intervention in Patients withCoronary Heart Disease |
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| GAO Ying-dong,XIA Yong-xiang,ZHANG Rui-sheng,ZHU Cheng-bin,ZHAO Xin-y,XIAO Ping-xi. Relationship Between Plasma IIA Secretory Phospholipase A2 andRestenosis after Percutanous Coronary Intervention in Patients withCoronary Heart Disease[J]. Progress in Modern Biomedicine, 2011, 11(19): 3666-3668 |
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| Authors: | GAO Ying-dong XIA Yong-xiang ZHANG Rui-sheng ZHU Cheng-bin ZHAO Xin-y XIAO Ping-xi |
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| Affiliation: | GAO Ying-dong1,XIA Yong-xiang1,ZHANG Rui-sheng1,ZHU Cheng-bin1,ZHAO Xin-ya1,XIAO Ping-xi2 (Nanjing Medical University,Affiliated Nanjing First Hospital,Department of 1.Clinical Laboratory,2.Cardiology.Nanjing,210006,China) |
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| Abstract: | Objective: To study the correlation between IIA-sPLA2 level and restenosis after percutanous coronary intervention(PCI) in Patients with coronary heart disease.Methods: This study enrolled 63 patients with coronary heart disease(CHD) who under-went successful PCI,39 patients with non-CHD,and 42 healthy subjects were studied as a control group.Levels of IIA-sPLA2 in plasma were measured by an enzymoimmunoassay using a monoclonal antibody.The patients who underwent PCI had repeat angiography at six-month foll... |
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| Keywords: | Group IIA secretory phospholipase A2 High sensitive C-reactive protein Percutanous coronary intervention Restenosis |
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