| 噬菌体抗体库构建技术在疾病防治中的应用 |
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| 引用本文： | 张聪敏,霍萍萍,赵宝华.噬菌体抗体库构建技术在疾病防治中的应用[J].生物技术通报,2011(10). |
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| 作者姓名： | 张聪敏 霍萍萍 赵宝华 |
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| 作者单位： | 河北师范大学生命科学学院,石家庄,050016 |
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| 基金项目： | 河北省自然科学基金项目(2009000290) |
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| 摘 要： | 噬菌体抗体库技术(phage antibody library)是近年发展的一项分子生物学新技术,近年来越来越多的学者利用这项技术获得目标抗体以应用于医疗制药及安全检测等多个领域.噬菌体抗体库技术的发展和应用,为抗体技术领域带来了巨大的变化,极大地推动了各种性能优良基因工程抗体的开发和应用.针对噬菌体抗体库构建的原理、方法、构建过程中所需考虑的因素以及在不同领域的应用作了综述.
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| 关 键 词： | 噬菌体抗体库 文库多样性 疾病防治 |
Phage Antibody Library Construction Technology and Its Application in Prevention and Cure of Disease |
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| Zhang Congmin,Huo Pingping,Zhao Baohua.Phage Antibody Library Construction Technology and Its Application in Prevention and Cure of Disease[J].Biotechnology Bulletin,2011(10). |
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| Authors: | Zhang Congmin Huo Pingping Zhao Baohua |
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| Institution: | Zhang Congmin Huo Pingping Zhao Baohua(College of Life Science,Hebei Normal University,Shijiazhuang 050016) |
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| Abstract: | Phage antibody library technology is a developing molecular biology technology in recent years,which a lot of scholars have used to obtain goal antibodies which are applied to medical pharmaceutical,safety testing.The development and application of Phage antibody library technology,has brought enormous changes to antibodies technology field,which also greatly promoted the research,development and application of kinds of genetic engineering of antibodies with excellent performance.This thesis has discussed a... |
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| Keywords: | Phage antibody library Library diversity Disease prevention and cure |
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