Predictive Value of a Profile of Routine Blood Measurements on Mortality in Older Persons in the General Population: The Leiden 85-Plus Study |
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| Authors: | Anne H. van Houwelingen Wendy P.J. den Elzen Simon P. Mooijaart Margot Heijmans Jeanet W. Blom Anton J. M. de Craen Jacobijn Gussekloo |
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| Affiliation: | 1Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands;2Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands;3Institute for Evidence-Based Medicine in Old Age (IEMO), Leiden, the Netherlands;Cardiff University, United Kingdom |
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| Abstract: | BackgroundVarious questionnaires and performance tests predict mortality in older people. However, most are heterogeneous, laborious and a validated consensus index is not available yet. Since most older people are regularly monitored by laboratory tests, we compared the predictive value of a profile of seven routine laboratory measurements on mortality in older persons in the general population with other predictors of mortality; gait speed and disability in instrumental activities of daily living (IADL).Conclusions/SignificanceIn the general population of oldest old, the number of abnormalities in seven routine laboratory measurements predicts five-year mortality as accurately as gait speed and IADL disability. |
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