(1) Center for Cellular and Molecular Biology, , Hyderabad, 500 007, India;(2) Reliance Life Sciences Pvt. Ltd., Fosbery Road, Sewree, Mumbai, 400 033, India
Abstract:
Background
Expression of transgenes in muscle by injection of naked DNA is widely practiced. Application of electrical pulses at the site of injection was demonstrated to improve transgene expression in muscle tissue. Zebrafish is a precious model to investigate developmental biology in vertebrates. In this study we investigated the effect of electroporation on expression of transgenes in 3–6 month old adult zebrafish.