1.Medical Clinic IV,Tübingen,Germany;2.University of Manchester,Manchester,UK;3.Boehringer Ingelheim Pharma KG,Biberach an der Riss,Germany
Abstract:
Background
Members of the Kinesin-3 family of kinesin-like proteins mediate transport of axonal vesicles (KIF1A, KIF1Bβ), distribution of mitochondria (KIF1Bα) and anterograde Golgi to ER vesicle transport (KIF1C). Until now, little is known about the regulation of kinesin-like proteins. Several proteins interact with members of this protein family. Here we report on a novel, KIF1 binding protein (KBP) that was identified in yeast two-hybrid screens.
