Proteins of Rapid Axonal Transport: Polypeptides Interacting with the Lectin from Lens Culinavis |
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Authors: | J-O Karlsson |
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Institution: | Institute of Neurobiology. University of Göteborg, Götrborg, Swedpn |
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Abstract: | Abstract: Rapidly transported fucose-labelled glycoproteins from axons of rabbit retinal ganglion cells were solubilized with nonionic detergents. The labelled glycoproteins carried hydrophobic sites as revealed by a reversible binding to a hydrophobic matrix. A major portion of the labelled glycoproteins carried α-D-mannopyranoside (or glucopyranoside) residues, as shown by a specific interaction with the lectin from Lens culinaris. Three major groups of labelled polypeptides capable of binding to the lectin are described. |
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Keywords: | Rapid axonal transport Lentil lectin |
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