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The cytotoxic norditerpene dilactones of Podocarpus milanjianus and Podocarpus sellowii |
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| Authors: | Johnny A Hembree Ciung-Jer Chang Jerry L McLaughlin John M Cassady Daniel J Watts Ernest Wenkert Sebastiko Ferreira Fonseca Jayr De Paiva Campello |
| Institution: | 1. Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907, U.S.A.;2. Department of Chemistry, Indiana University, Bloomington, IN 47401, U.S.A.;3. Instituto de Quimica, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil |
| Abstract: | The cytotoxic norditerpene dilactones nagilactone F and its new congener nagilactone G have been isolated from the bark constituents of Podocarpus milanjianus and Podocarpus sellowii. The diterpenes totarol, 19-oxototarol and macrophyllic acid were also isolated. |
| Keywords: | Podocarpaceae bark norditerpene dilactones 9KB cytotoxicity structural analysis nagilactone F nagilactone G |
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