Prevalence of class 1 integron among multidrug-resistant Acinetobacter baumannii in Tabriz, northwest of Iran |
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| Authors: | Peymani Amir Farajnia Safar Nahaei Mohammad Reza Sohrabi Nasrollah Abbasi Laleh Ansarin Khalil Azhari Fatemeh |
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| Institution: | Department of Microbiology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. |
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| Abstract: | Integrons are associated with a variety of gene cassettes, which confer resistance to multiple classes of antibacterial drugs. In this study we tested the frequency of class 1 and 2 integrons among multidrug-resistant Acinetobacter baumannii (MDRAB) clinical isolates. One hundred clinical isolates of A. baumannii were screened for carriage of class 1 and 2 integrons by PCR method. Results showed that seventy four (92.5%) of 80 MDRAB carried class 1 integron. Integron-positive isolates were statistically more resistant to aminoglycoside, quinolone and beta-lactam compounds except for cefepime. This is the first report of class 1 integrons in MDRAB isolates in northwest Iran. |
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