Mutational analysis of the carboxyl terminus of the Moloney murine leukemia virus integration protein. |
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| Authors: | M J Roth |
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| Affiliation: | Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854-5635. |
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| Abstract: | The integration protein (IN) is required for retrovirus DNA integration into the host DNA. The function of the C terminus of the Moloney murine leukemia virus IN protein was examined. The terminal 28 amino acids were found to be nonessential. A linker insertion at position 6025, within a 36-amino-acid insertion not found in any other retrovirus, also produced viable virus. |
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