| 细胞周期与细胞凋亡 |
| |
| 引用本文： | 周明华 陈思颖. 细胞周期与细胞凋亡[J]. 生理科学进展, 1996, 27(4): 319-323 |
| |
| 作者姓名： | 周明华 陈思颖 |
| |
| 作者单位： | 香港大学医学院解剖学系 |
| |
| 基金项目： | GrowthFactor公司资助 |
| |
| 摘 要： | 从海洋生物胚胎细胞到哺乳动物的细胞周期，主要是在其细胞周期基因产物周期素及Ｐ３４的调控下启动，运行和脱出周期的；某些原癌基因或抑癌基因的产物如ｐ５３，ｐＲＢ也直接调控着细胞周期。
|
| 关 键 词： | 细胞周期 细胞 细胞凋亡 |
Cell Cycle and Apoptosis |
| |
| CHAU RMW,CHAN SSW,LI MF, WU XY. Cell Cycle and Apoptosis[J]. Progress in Physiological Sciences, 1996, 27(4): 319-323 |
| |
| Authors: | CHAU RMW CHAN SSW LI MF WU XY |
| |
| Abstract: | The progression of cell cycle in embryonic cells from oceanic bionts to mammalians is initiated, promoted and terminated under the regulation of cell cycle gene products,named cyclins,and a p34 (cdc 2 ). Besides, oncogene(proto-oncogene)products such as p53 and pRB also directly regulate the progression of cell cycle, Howeverf the p34(cdc 2)which promotes the mitotic cell division also initiates the apoptosis of certain cells.Therefore, mutations of genes that regulate the normal progression of cell cycle would cause cells in the cell cycle undergoing either apoptosis or uncontrollable proliferation. |
| |
| Keywords: | Cell cycle Apoptosis Programmed cell death Cylin Death gene |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
