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巴氏碳球C60光激发对红细胞膜流动性的影响
引用本文:黄文栋,李文铸.巴氏碳球C60光激发对红细胞膜流动性的影响[J].生物化学与生物物理学报,1996,28(3):321-324.
作者姓名:黄文栋  李文铸
作者单位:浙江大学生物科学与技术系,渐江大学物理系
基金项目:国家科委重点课题基金,浙江省自然科学基金
摘    要:巴氏碳球C_(60)光激发对红细胞膜流动性的影响黄文栋,钱凯先,唐海琼(浙江大学生物科学与技术系,杭州310027)李文铸(渐江大学物理系,杭州310027)关键词C_(60);光激发;红细胞膜;荧光偏振;膜流动性C60是Kroto等人[1]于1985...

关 键 词:红细胞膜  光激光  膜流动性  碳60

The Effect of Buckyball C_(60) Irradiation on the Fluidity of Erythrocyte Membranes
HUANG Wen-Dong, QIAN Kai-Xian and TAN Hai-Qiong.The Effect of Buckyball C_(60) Irradiation on the Fluidity of Erythrocyte Membranes[J].Acta Biochimica et Biophysica Sinica,1996,28(3):321-324.
Authors:HUANG Wen-Dong  QIAN Kai-Xian and TAN Hai-Qiong
Abstract:The erythrocyie membranes were prepared from fresh human blood and 1, 6-diphenyl-1, 3, 5-hexatriene (DPH) was used as a probe to detect their change of fluidity. It was found that after brief irradiation, C60 remarkably increases the degree of fluorescence polarization of the DPH-labeled erythrocyte membrane,suggesting that C60 irradiation could greatly reduce the fluidity of erythrocyte membrane.It was also found that the reduction of membrane fluidity was mainly due to the oxidation of sulfhydry groups in the membrane protein and the peroxidation of membrane unsaturated fatty acids.
Keywords:C_(60)  Irradiation  Erythrocyte membrane  Fluorescence polarization  Membrane fluidity
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