Mtmr8 is essential for vasculature development in zebrafish embryos |
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Authors: | Jie Mei Sha Liu Zhi Li Jian-Fang Gui |
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Affiliation: | (1) State Key Laboratory of Freshwater Ecology and Biotechnology, Center for Developmental Biology, Institute of Hydrobiology, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Wuhan, 430072, China |
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Abstract: | Background Embryonic morphogenesis of vascular and muscular systems is tightly coordinated, and a functional cooperation of Mtmr8 with PI3K in actin filament modeling and muscle development has been revealed in zebrafish. Here, we attempt to explore the function of Mtmr8 in vasculature development parallel to its function in muscle development. |
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