Cerebroside analogues from 3-phenylserines |
| |
Authors: | Benjamin Weiss |
| |
Affiliation: | 1. Division of Neuroscience, New York State Psychiatric Institute, Department of Biochemistry, College of Physicians and Surgeons, Columbia University, New York, N.Y. 10032, USA;2. Institute for Neurochemistry and Drug Addiction, Rockland Research Institute, Ward''s Island, N.Y. 10035, USA |
| |
Abstract: | Cerebroside analogues were synthesized from DL-threo-and DL-erythro-3-phenylserines by the following sequence of reactions: estirification, N-acylation, reduction with sodium bis (2-methoxyethoxy)-aluminum hydride (SMEAH), and condensation with acetobromoglucose followed by deacetylation. Mass spectrometry disclosed that the glycosidic bond was formed at the primary hydroxyl group. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|