Rate of DNA replication fork movement within a single mammalian cell |
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Authors: | Yury B Yurov |
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Institution: | Institute of Medical Genetics of AMS USSR Kashirskoye shosse 6a, Moscow 115478, USSR |
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Abstract: | Autoradiography of replicating DNA molecules isolated from individual human cells shows that the rate of DNA replication fork movement within a single cell varies from 0.2 to 1.2 μm/min with an average value of 0.5 to 0.6 μm/min. These data suggest that replication forks move at substantially different rates in different parts of the genome within a single cell. |
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