Plasma membrane redox activity correlates with N-myc expression in neuroblastoma cells. |
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Authors: | M A Medina A del Castillo-Olivares L Schweigerer |
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Institution: | Sektion Onkologie/Immunologie, Ruprecht-Karls-Universit?t, Heidelberg, Germany. |
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Abstract: | In different neuroblastoma cell lines and transfected clones, an increasing plasma membrane redox activity correlates with amplification and enhanced expression of the N-myc oncogene. Furthermore, plasma membrane redox activity is partially inhibited by retinoic acid in neuroblastoma cells with multiple copies of the N-myc oncogene but not in neuroblastoma cells with only one copy of this gene. |
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