| Candida albicans hyphal invasion: thigmotropism or chemotropism? |
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| 引用本文： | Davies JM,Stacey AJ,Gilligan CA. Candida albicans hyphal invasion: thigmotropism or chemotropism?[J]. FEMS microbiology letters, 1999, 171(2): 245-249. DOI: 10.1016/S0378-1097(98)00600-4 |
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| 作者姓名： | Davies JM Stacey AJ Gilligan CA |
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| 摘 要： |
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| 收稿时间： | 1998-10-30 |
Candida albicans hyphal invasion: thigmotropism or chemotropism? |
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| Davies J M,Stacey A J,Gilligan C A. Candida albicans hyphal invasion: thigmotropism or chemotropism?[J]. FEMS microbiology letters, 1999, 171(2): 245-249. DOI: 10.1016/S0378-1097(98)00600-4 |
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| Authors: | Davies J M Stacey A J Gilligan C A |
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| Affiliation: | Department of Plant Sciences, University of Cambridge, UK. jmd32@cam.ac.uk |
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| Abstract: | Hyphae of the human pathogenic fungus Candida albicans exhibit thigmotropic behaviour in vitro, in common with phytopathogenic and saprotrophic fungi. An examination of the literature on C. albicans hyphal penetration of epithelial and endothelial membranes does not support the premise that hyphal thigmotropism plays a major role in tissue invasion. Further experimentation is now required to assess thigmotropic behaviour on host membranes and vaginal epithelial cells are suggested as a test model. It is proposed that while thigmotropism may and invasion of tissue invaginations, chemotropism can explain C. albicans hyphal invasion patterns of both endothelium and epithelium. |
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| Keywords: | Candida albicans Chemotropism Invasive hypha Thigmotropism |
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