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Myeloid dendritic cells correlate with clinical response whereas plasmacytoid dendritic cells impact autoantibody development in rheumatoid arthritis patients treated with infliximab |
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| Authors: | Christophe Richez Thierry Schaeverbeke Chantal Dumoulin Joël Dehais Jean-François Moreau Patrick Blanco |
| Institution: | 1. Département de Rhumatologie, CHU Bordeaux, place Amélie Raba-Léon, 33076, Bordeaux, France 2. UMR-CNRS 5164, Université Bordeaux 2, 146 rue Léo Saignat, 33076, Bordeaux, France 3. Département de Virologie et d'Immunologie biologique, CHU Bordeaux, place Amélie Raba-Léon, 33076, Bordeaux, France 4. Service de Médecine Interne, CHU Bordeaux, 1 Avenue de Magellan, 33600, Pessac, France |
| Abstract: | IntroductionThe objective of our study was to identify the significance of the subtypes of dendritic cell (DC), specifically myeloid DCs (mDCs) and plasmacytoid DCs (pDCs), in rheumatoid arthritis (RA) pathogenesis through their longitudinal follow-up in patients receiving infliximab. |
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