Study of structure of secretory 28 kDa protein from the rat olfactory epithelium |
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Authors: | Andreeva S G Merkulova M I Shuvaeva T M Novoselov V I Peshenko I V Novoselov S V Fesenko E E Lipkin V M |
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Affiliation: | Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. |
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Abstract: | Clone lambda a26.1 isolated from rat olfactory epithelium contains a full-length 28-kDa protein cDNA (1414 b.p.). The reconstructed protein sequence comprises 223 aa with a calculated molecular mass of 24,630 Da. A substantial homology was revealed between the amino acid sequence of the 28-kDa protein and those of thiol-specific antioxidants (peroxiredoxines). The 28-kDa protein belongs to the 1 Cys-subfamily of peroxiredoxines and is the first member of peroxiredoxines identified in the olfactory epithelium. |
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